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What is Testosterone Replacement Therapy?
An overview of TRT — what it is, who it's for, and what to expect from treatment.
Testosterone Replacement Therapy (TRT) is a medically supervised treatment designed to restore testosterone to healthy physiological levels in men who produce insufficient amounts on their own. Low testosterone — clinically referred to as hypogonadism — affects an estimated 10–40% of men over 45 and can significantly impact quality of life.
Common symptoms include persistent fatigue, reduced libido, difficulty building or maintaining muscle, increased body fat, mood disturbances such as irritability or low mood, and cognitive fog. Many men normalise these changes as simply "getting older," but they are frequently a direct consequence of hormonal deficiency that responds well to treatment.
TRT works by supplementing the testosterone your body is no longer producing in adequate quantities. The most common delivery method is weekly or bi-weekly subcutaneous or intramuscular injections of testosterone cypionate. This approach provides predictable, stable hormone levels compared to gels or patches, which can have absorption variability.
Before starting treatment, every patient undergoes comprehensive bloodwork to confirm the diagnosis and establish a baseline. We measure total testosterone, free testosterone, LH, FSH, haematocrit, PSA, and a full metabolic panel. Treatment is only recommended when blood work and symptoms align — we do not treat numbers in isolation.
Most patients report meaningful improvements in energy and libido within four to six weeks. Body composition changes — reduced fat, increased lean mass — typically become apparent over three to six months with consistent training. Ongoing quarterly lab monitoring ensures your treatment remains safe and optimally dosed throughout.